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Melatonin During a Cut: Does It Help?

Editorial Team · Section: Sports Nutrition: New Angles · Reading time: 6 min
Melatonin During a Cut: Does It Help?
Photo: Jp Valery / Unsplash

Anyone who has dieted down for a competition or a summer cut knows the pattern: hunger at night, restless sleep, early waking and dragging through morning workouts. Melatonin is cheap and widely available in the US, so many dieters try it. Our editorial team looked at whether it actually helps during a calorie deficit, and what it can and cannot do.

Why sleep tends to suffer on a diet

A sustained energy deficit changes hormones that regulate appetite and arousal. Leptin falls, ghrelin rises, and the body becomes more alert to food cues, which made evolutionary sense when food was scarce. Many dieters report trouble falling asleep, lighter sleep and waking hungry in the early morning hours.

Other factors add up during a cut. People often increase cardio, sometimes late in the evening, and rely more heavily on caffeine or stimulant-containing pre-workouts to push through low energy. Both can delay sleep onset if used too late in the day.

Poor sleep is not just uncomfortable; it affects the outcome of the diet. In a well-known study by Nedeltcheva and colleagues (2010), dieters who slept 5.5 hours per night lost a similar amount of weight as those who slept 8.5 hours, but a much larger share of the loss came from fat-free mass rather than fat. Hunger was also higher with short sleep.

This means that protecting sleep during a cut is not a minor detail. It may influence how much muscle is preserved and how manageable hunger feels, both of which matter for physique athletes and lifters.

What melatonin is and what it does

Melatonin is a hormone produced mainly by the pineal gland in response to darkness. Its levels rise in the evening, peak in the middle of the night and fall toward morning. It acts as a timing signal for the circadian system rather than as a sedative in the classic sense.

In the United States, melatonin is sold as a dietary supplement without a prescription, while in the EU, the UK and several other countries it is regulated as a medicine. Use among US adults has grown substantially, as documented by Li and colleagues (2022), who reported a several-fold increase over two decades.

A meta-analysis by Ferracioli-Oda, Qawasmi and Bloch (2013) found that melatonin reduced the time to fall asleep and modestly increased total sleep time in people with primary sleep disorders. The effects were statistically significant but small, in the range of several minutes for sleep onset.

Melatonin is most useful for problems of timing: jet lag, shift work and delayed sleep phase. It is less effective for insomnia driven by stress, pain or hunger, which are exactly the factors that often disrupt sleep during a diet.

Sleep problemLikely benefit from melatoninBetter first steps
Jet lag, travel to competitionsGoodLight exposure planning
Delayed sleep timingModerateConsistent schedule, morning light
Night-time hungerLowMeal timing, protein before bed
Stimulant-related insomniaLowEarlier caffeine cutoff
Anxiety, stressLowStress management, professional help
Melatonin During a Cut: Does It Help? — illustration
Photo: Chris Ralston / Unsplash

Does melatonin affect body composition or appetite?

Animal studies suggest that melatonin may influence energy metabolism, brown fat activity and body weight. These findings have fueled interest in melatonin as a weight-loss aid, but rodents are nocturnal and their responses to melatonin differ from those of humans.

A systematic review and meta-analysis by Delpino and colleagues (2021) of randomized trials found that melatonin supplementation was associated with small reductions in body weight and body mass index in some analyses, but the overall effects on body composition were modest and inconsistent. Many included trials were small and involved people with obesity or metabolic disease.

One trial by Szewczyk-Golec and colleagues (2017) in obese patients on a calorie-restricted diet found that adding melatonin lowered markers of oxidative stress and influenced adipokines. These changes were biochemical; they did not translate into dramatic additional fat loss.

Energy deficit Protein and training Sleep duration Melatonin supplement
Figure 1. Schematic illustration of relative importance for fat-loss outcomes; not based on measured effect sizes.

The realistic view is that melatonin does not burn fat in any meaningful sense. Its potential value during a cut lies in helping some people fall asleep more easily, which may indirectly support muscle retention and appetite control.

Product quality and timing in the US market

Because melatonin is a supplement in the US, actual content can differ substantially from the label. An analysis by Cohen and colleagues (2023) published in JAMA found that most melatonin gummies sold in the US contained amounts that differed from the label, ranging from roughly three-quarters to more than three times the stated dose. An earlier Canadian study by Erland and Saxena (2017) found similar variability and, in some products, serotonin contamination.

For this reason, products verified by independent testing, such as those carrying the USP Verified mark, are preferable. Low doses are often as effective as high ones for circadian purposes, and many US products contain doses of 5–10 mg, well above what is typically needed.

Timing matters as much as dose. For sleep onset, melatonin is usually taken 30–60 minutes before the intended bedtime. For shifting the body clock, smaller doses taken several hours before habitual sleep may be used, ideally under guidance from a sleep specialist.

Melatonin may slightly impair glucose tolerance when taken close to a meal. A study by Rubio-Sastre and colleagues (2014) showed reduced glucose tolerance after acute melatonin administration. During a cut, it is therefore sensible not to take melatonin together with a large late-night carbohydrate meal.

Safety and smarter alternatives during a cut

Short-term melatonin use is generally well tolerated. Common side effects include morning grogginess, headache, dizziness and vivid dreams. Long-term safety data are more limited, especially for high doses used nightly for years.

Melatonin can interact with blood thinners, blood pressure medications, diabetes drugs, immunosuppressants and sedatives. People with epilepsy, autoimmune disease or depression, as well as pregnant and breastfeeding women, should consult a doctor first. It should not be combined with alcohol.

Before reaching for supplements, dieters can try several evidence-based strategies:

Disclaimer. This article is for informational purposes only and is not a substitute for medical advice. If you experience persistent insomnia, consult a physician. Do not combine melatonin with prescription medications without discussing it with your doctor or pharmacist.

Conclusions of the editorial team

Sleep often worsens during a calorie deficit, and short sleep can shift weight loss toward muscle rather than fat. Protecting sleep is a legitimate goal during a cut.

Melatonin has small effects on sleep onset and no meaningful direct fat-burning effect. It may help some dieters with sleep timing, but it does not address hunger or stimulant-related insomnia. Low doses from verified products are the sensible choice if it is used at all.

For more on this topic, we recommend our articles on diet breaks and refeeds, on caffeine and sleep in athletes, and on preserving muscle during fat loss.

References

  1. Nedeltcheva AV, Kilkus JM, Imperial J, Schoeller DA, Penev PD. Insufficient sleep undermines dietary efforts to reduce adiposity. Ann Intern Med. 2010;153(7):435–441.
  2. Ferracioli-Oda E, Qawasmi A, Bloch MH. Meta-analysis: melatonin for the treatment of primary sleep disorders. PLoS One. 2013;8(5):e63773.
  3. Li J, Somers VK, Xu H, Lopez-Jimenez F, Covassin N. Trends in use of melatonin supplements among US adults, 1999–2018. JAMA. 2022;327(5):483–485.
  4. Delpino FM, Figueiredo LM, Nunes BP. Effects of melatonin supplementation on body composition: a systematic review and meta-analysis of randomized clinical trials. Clin Nutr. 2021;40(7):4595–4605.
  5. Cohen PA, Avula B, Wang YH, Katragunta K, Khan I. Quantity of melatonin and CBD in melatonin gummies sold in the US. JAMA. 2023;329(16):1401–1402.
  6. Erland LA, Saxena PK. Melatonin natural health products and supplements: presence of serotonin and significant variability of melatonin content. J Clin Sleep Med. 2017;13(2):275–281.
  7. Rubio-Sastre P, Scheer FA, Gómez-Abellán P, Madrid JA, Garaulet M. Acute melatonin administration in humans impairs glucose tolerance in both the morning and evening. Sleep. 2014;37(10):1715–1719.
  8. https://masscraftusa.com/halotestin-5-mg-hilma-biocare-33524-us
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